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Eric Overström

Eric Overström

Professor Overström, a developmental biologist, is a member of the faculty at Tufts University, the School of Veterinary Medicine in North Grafton, Massachusetts, the Department of Anatomy & Cellular Biology, Tufts University School of Medicine, Boston, and the Program in Cell, Molecular and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Boston. He received his Ph.D. in Reproductive Physiology from the University of Massachusetts/Amherst in 1981 and subsequently trained as a postdoctoral research fellow at the Laboratory for Human Reproduction & Reproductive Biology at Harvard Medical School in Boston prior to joining the Tufts faculty.

Application of Cloning to the Production of Biopharmaceuticals to Treat Human and Animal Disease

Research in his laboratory focuses on both fundamental studies of preimplantation stage embryos of domestic (goats, cattle, pigs) and laboratory animals (rodents), and applied studies to improve reproductive efficiency in these species. With respect to the former, his laboratory engaged in fundamental research focused on cell and molecular mechanisms of early embryo development, including the production of transgenic and cloned animals, in species including the pig, cow, goat and rodents. Current research is directed at understanding 1) cell cycle synchronicity of cytoplasts and karyoplasts in cloned embryos produced by somatic cell nuclear transfer (NT) and 2) activation-induced interactions between meiotic spindle-associated factors and the cytoplasm on their role in establishing developmental competence of the bovine, caprine and murine nuclear transfer (NT) embryo. With respect to the latter, the lab has been successful in producing transgenic swine and mice, and more recently the laboratory reported the production of the first cloned transgenic goats using novel somatic cell nuclear transfer methods (Baguisi et al, 1999). Moreover, this work has since led to the development of improved methods for cloning mice with success rates >25%.

Image: Eric Overström

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Topic Sets Available

AAAS Report on Stem-Cells

AstroTheology: Religious Reflections on Extraterrestrial Life Forms

Agency: Human, Robotic and Divine
Becoming Human: Brain, Mind, Emergence
Big Bang Cosmology and Theology (GHC)
Cosmic Questions CD-ROM Preview...
Cosmic Questions Interviews

Cosmos and Creator
Creativity, Spirituality and Computing Technologies
CTNS Content Home
Darwin: A Friend to Religion?
Demystifying Information Technology
Divine Action (GHC)
Dreams and Dreaming: Neuroscientific and Religious Visions'
E. Coli at the No Free Lunchroom
Engaging Extra-Terrestrial Intelligence: An Adventure in Astro-Ethics
Evangelical Atheism: a response to Richard Dawkins
Ecology and Christian Theology
Evolution: What Should We Teach Our Children in Our Schools?
Evolution and Providence
Evolution and Creation Survey
Evolution and Theology (GHC)
Evolution, Creation, and Semiotics

The Expelled Controversy
Faith and Reason: An Introduction
Faith in the Future: Religion, Aging, and Healthcare in the 21st Century

Francisco Ayala on Evolution

From Christian Passions to Scientific Emotions
Genetic Engineering and Food

Genetics and Ethics
Genetic Technologies - the Radical Revision of Human Existence and the Natural World

Genomics, Nanotechnology and Robotics
Getting Mind out of Meat
God and Creation: Jewish, Christian, and Muslim Perspectives on Big Bang Cosmology
God, Humanity and the Cosmos: A Textbook in Science and Religion
God the Spirit - and Natural Science
Historical Examples of the Science and Religion Debate (GHC)
History of Creationism
Intelligent Design Coming Clean

Issues for the Millennium: Cloning and Genetic Technologies
Jean Vanier of L'Arche
Nano-Technology and Nano-ethics
Natural Science and Christian Theology - A Select Bibliography
Neuroscience and the Soul
Outlines of the Science and Religion Debate (GHC)

Perspectives on Evolution

Physics and Theology
Quantum Mechanics and Theology (GHC)
Questions that Shape Our Future
Reductionism (GHC)
Reintroducing Teleology Into Science
Science and Suffering

Scientific Perspectives on Divine Action (CTNS/Vatican Series)

Space Exploration and Positive Stewardship

Stem-Cell Debate: Ethical Questions
Stem-Cell Ethics: A Theological Brief

Stem-Cell Questions
Theistic Evolution: A Christian Alternative to Atheism, Creationism, and Intelligent Design...
Theology and Science: Current Issues and Future Directions
Unscientific America: How science illiteracy threatens our future
Will ET End Religion?

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