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José Cibelli. Vice President of Research, Advanced Cell Technology
- Transgenic ES-like cells were injected into preimplantation embryos and
transferred into surrogate mothers
- Six out of seven animals born were found onimeric for at least one tissue
and overall onimerism was detected in derivatives from the three germ
layers: actoderm, mesoderm and endoderm
- In bovine, embryonic pluripotent cells can be generated from somatic cells
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Chapter II: Human studies
Human ES cells.
Thomson et al 1998
Science vol282 1145-1147
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- Differentiation was induced by injection of cell into immuno-deficient
mice
- Two months after injection, teratomas were produced that included bone,
muscle, gut, kidney neurons
- For transplantation therapies, a pure population of cells must be obtained
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Email
link | Feedback | Contributed by: Boston University. Video adapted from the
Issues for the Millennium Workshop
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