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The Clinical Potentials for Stem Cell Products

The economic and psychological tolls of chronic, degenerative, and acute diseases in the United States are enormous. It has been estimated that up to 128 million people suffer from such diseases; thus, virtually every citizen is effected directly or indirectly.This approximation is based on aggregate counts from various sources compiled by the Alliance for Aging Research, Washington, DC. The total costs of treating diabetes, for example is approaching $100 billion in the United States alone.This number includes a "lost productivity" calculation, but does not include costs associated with diseases that are not classically secondary to diabetes, but are associated with immune system... As more research takes place, the developmental potential of different kinds of stem cells will become better understood. As the science is understood now, adult stem cells are limited in their potential to differentiate. Embryonic germ cells have a great differentiation capacity, and embryonic stem cells are thought to be able to differentiate into almost any tissue. Thus, different types of stem cells could have different applications. Below is a discussion of potential stem cell applications.

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Go to Genetics Topic Index
Stem Cell Research and Applications: Monitoring the Frontiers of Biomedical Research
Preface
Findings and Recommendations
The Science of Stem Cell Research and Potential Therapies
     Current Status of Human Stem Cell Research
     Sources and Characteristics of Human Stem Cells
        Human Embryonic Stem Cells
        Human Embryonic Germ Cells.
        Human Adult Stem Cells
     The Clinical Potentials for Stem Cell Products
     Some Examples of Treatments for Major Diseases
        Type 1 Diabetes in Children
        Nervous System Diseases
        Primary Immunodeficiency Diseases
        Diseases of Bone and Cartilage
        Cancer
     Uses in Research
        A New Window on Human Developmental Biology
        Models of Human Disease that are Constrained by Current Animal and Cell Culture Models
        Transplantation
        Gene Therapy
Spiritual and Religious Contexts
Ethical Concerns
     The Moral Status of Human Stem Cells
     Moral Issues Surrounding the Sources of Stem Cells
Sources of Stem Cells and Guidelines for Use
Justice Considerations
Funding
Oversight and Accountability
     Private Sector Oversight
     Intellectual Property Considerations
     Public Sector Oversight
Conclusion
Appendix I: Working Group Members
Appendix II: Staff
Appendix III: About AAAS and ICS

Source:

Audrey R. Chapman, Ph.D., Mark S. Frankel, Ph.D., and Michele S. Garfinkel, Ph.D. for the American Association for the Advancement of Science and The Institute for Civil Society

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