William C. Mobley, M.D., Ph.D.is Professor
and Chair of the Department of Neurology and Neurological Sciences at
. After completing undergraduate training in chemistry and zoology at the
, Mobley received the medical degree and doctorate in neuroscience from
. He trained in pathology and pediatrics at the
and completed a residency and fellowship in neurology at
, where he also was chief resident in pediatric neurology. In 1985, he joined
the faculty of the
, San Francisco School of Medicine where he rose to the rank of professor of
neurology, pediatrics and the neuroscience program and served as the director of
child neurology. In 1991, he was named Derek Denny Brown Scholar of the American
Neurological Association. Since 1997 he has been the Chair of the Department of
Neurology and Neurological Sciences at
and holds the John E. Cahill Family Endowed Chair. He also serves as
co-Director of the Stanford Brain Research Institute. His laboratory studies the
signaling biology of neurotrophic factors in the normal brain and in animal
models of neurodegenerative disorders, such as Alzheimer's disease and Down
syndrome. He is the recipient of both the Zenith Award and the
from the Alzheimer's Association and is a Fellow of the Royal College of
Physicians. Mobley serves as Editor of the Neurobiology
of Disease, as a member of the American Society for Experimental
Neurotherapeutics, was former president of the Association of University
Professors of Neurology and president-elect of The Professors of Child
Sofroniew, M, C. Howe and W. C. Mobley. Nerve
Growth Factor Signaling, Neuroprotection and Neurorepair. Annual
Review of Neuroscience: 2001.
Lynch, C. and W. C. Mobley. Comprehensive
Theory of Alzheimer's Disease: The Effects of Cholesterol on Membrane Receptor
Trafficking. Annals of the New York Academy of Sciences: 2000.
Cooper, J. D. and W. C. Mobley. Neurotrophic
Factors as Potential Therapeutic Agents in Neuronal Ceroid Lipofuscinosis.
In: Batten Disease: Diagnosis, Treatment and Research. Academic Press:
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